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The formal pronunciation of omeprazole is: o-me-pra-zole. To help you understand the pronunciation better, let s break it down into individual syllables: o (as in oh ) me (as in meat ) pra (as in prance ) zole (rhymes with soul ) Remember to emphasize the zole part at the end. 2. Informal Pronunciation of Omeprazole. baclofen restless leg syndrome How To Pronounce Omeprazole Pronunciation Of Omeprazole. 3 years ago more. Isabella Saying. 10.9K. TikTok video from Pharmify. 8.8M. Omeprazole key